1. In anatomy, perforated by one or more openings: The tissues Dr. Blacks showed his students were all fenestrated with holes of different sizes. 2. Made with windows or similar openings in a building: When Mr. and Mrs. White had their house built for them, they were happy to have so many big fenestrated walls, and even one fenestrated part in the roof!
3. Regarding something that has openings or perforations: The woolen coat that Mrs. Green had, had so many fenestrated spots where some moths had eaten away!
4. A description of a lepidopteran's wings that have transparent markings: Sam enjoyed looking at the beautiful butterfly with fenestrated wings.